TSH

Product Features

  • No need for shaker
  • Calibrated to WHO international Standard
  • Single - step test method
  • 48 , 96 , 192 test packages
  • Ready to use solutions

Product Catalog

Thyroid-stimulating hormone (TSH or thyrotropin) is a glycopolipeptide hormone synthesized and secreted by the anterior pituitary gland which regulates the endocrine function of the thyroid gland

TSH consists of two subunits, the alpha and the beta subunit. The α subunit is identical to that of human chorionic gonadotropin (HCG), luteinising hormone (LH), follicle-stimulating hormone (FSH). The β (beta) subunit is unique to TSH, and therefore determines its function. TSH production is controlled by a Thyrotropin Releasing Hormone, (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus, and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). Release of TSH is regulated by the circulating free fraction of thyroid hormones in the blood. TSH levels are depressed when peripheral concentrations of the free fraction of thyroid hormones are high

Conversely, TSH levels are high when peripheral concentrations of thyroid hormones are low. This effect creates a regulatory negative feedback loop. TSH levels are tested in the blood of patients suspected of suffering from excess (hyperthyroidism), or deficiency (hypothyroidism) of thyroid hormone. Generally, a normal range for TSH is between 0.3 and 3.0 mIU/mL, but the interpretation

Required Information About TSH
Assay Type Antibody Sandwich
Conjugate Solution Anti-TSH-Biotin, Anti-TSH-HRP Ready To Use
Chromogen- Substrate Tetramethylbenzidine (TMB) and hydrogen peroxide Ready To Use
Incubation time 45 + 15 min Room temperature
Standards μl IU/ml 0.0 ,2.5 ,5.0, 10, 25 Ready To Use
Required Samplers μl 50,100
Control serum 1 Normal control Ready To Use
Stop Solution Hydrochloric acid(1M) Ready To Use
Wash Solution PBS - Tween (1vial, 30 ml concentrated,20x)
Plate Streptavidin Coated Wells 48 - 96
Sensitivity μl IU/ml 0.05
Hook effect UP TO μl IU/ml 400

Product Features

  • No need for shaker
  • Calibrated to WHO international Standard
  • Single - step test method
  • 48 , 96 , 192 test packages
  • Ready to use solutions

Product Catalog