T4

Product Features

  • No need for shaker
  • Calibrated to WHO international Standard
  • Single - step test method
  • 48 , 96 , 192 test packages
  • Ready to use solutions

Product Catalog

The thyroid hormone, thyroxine (T4) is produced by the thyroid gland. An important component in the synthesis is iodine. The major form of thyroid hormone in the blood is thyroxine (T4). Thyroxine is converted to the active T3 (three to four times more potent than T4) within cells by deiodinases (5′- iodinase). Thyroxine-binding globulin (TGB) is the major carrier protein for circulating thyroid hormone. Only a very small fraction of the circulating hormone is free (unbound) – T4 0.03%. The thyronines act on the body to increase the basal metabolic rate, affect protein synthesis and increase the body’s sensitivity to catecholamines (such as adrenaline) by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds. Numerous physiological and pathological stimuli influence thyroid hormone synthesis. Thyrotoxicosis or hyperthyroidism is the clinical syndrome caused by an excess of circulating free thyroxine, free triiodothyronine, or both. Both T3 and T4 are used to treat thyroid hormone deficiency (hypothyroidism).

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Required Information About T4
Assay Type Competitive
Conjugate Solution T4-HRP Ready To Use
Chromogen- Substrate Tetramethylbenzidine (TMB) and hydrogen peroxide Ready To Use
Incubation time 45 + 15 min Room temperature
Standards µg/dl 0.0 ,2.5 ,5.0 ,10 ,15 ,30 Ready To Use
Required Samplers μll 25 ,50 ,100
Control serum 1 Normal control Ready To Use
Stop Solution Hydrochloric acid(1M) Ready To Use
Wash Solution PBS - Tween (1vial, 30 ml concentrated,20x)
Plate coated with monoclonal anti -T4 Wells 48 - 96 -192
Sensitivity µg/dl 0.2

Product Features

  • No need for shaker
  • Calibrated to WHO international Standard
  • Single - step test method
  • 48 , 96 , 192 test packages
  • Ready to use solutions

Product Catalog